CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. CD1 antigens are expressed on cortical thymocytes, but not on mature T cells. This often remains true in neoplastic cells from these populations, so that the presence of CD1 antigens can be used in diagnostic immunohistochemistry to identify some thymomas and malignancies arising from T cell precursors.
Abbkine CD1 Monoclonal Antibody affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody can react with Human，Mouse and Rat samples. It was tested in IHC-p and IF. The concentration of the antibody is 1mg/ml. Optimal working dilutions should be determined experimentally by the investigator.
Our group wanna detect CD1 proteins in mouse heart tissue. We adopted Immunohistochemical analysis in part of our research. One of my colleagues recommended Abbkine products to me, and the product didn’t not disappoint me. We got a strong signal and the signal was localizing where we expect it to. I’ll choose Abbkine again.
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